Description

2-(2-Chloro-Benzoyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and cardiovascular disorders. It is primarily required by R&D laboratories and manufacturing facilities in the pharmaceutical and biotechnology sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates and novel therapeutic agents.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• API Synthesis: Serves as a core scaffold for constructing complex molecules with potential biological activity in preclinical and clinical development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Academic Research: Utilized in university and institutional labs for studying organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-(2-Chloro-Benzoyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
CAS No.	1009695-46-8
Molecular Formula	C₁₇H₁₄ClNO₃
Molecular Weight	315.75 g/mol
Synonyms	2-[(2-Chlorophenyl)carbonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 2-(2-Chlorobenzoyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 1,2,3,4-Tetrahydro-2-(2-chlorobenzoyl)-3-isoquinolinecarboxylic Acid; 1009695-46-8; 2-(2-Chloro-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-Benzoyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client requirements or internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.