Description

2-(5-Bromo-2-Ethoxy-Benzenesulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is critical for research and development in medicinal chemistry, serving as a key building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of complex, target-specific Active Pharmaceutical Ingredients (APIs) requiring a tetrahydroisoquinoline sulfonamide moiety.
• Chemical Biology Probes: Serves as a starting material for creating specialized molecular probes to study enzyme function and biological pathways.
• Process Development: Used in scaling up and optimizing synthetic routes from laboratory to pilot plant scale for potential commercial manufacturing.

Basic Information

Product Name	2-(5-Bromo-2-Ethoxy-Benzenesulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
CAS No.	1008962-07-9
Molecular Formula	C18H18BrNO5S
Molecular Weight	440.31 g/mol
Synonyms	1,2,3,4-Tetrahydro-2-[(5-bromo-2-ethoxyphenyl)sulfonyl]-3-isoquinolinecarboxylic Acid; 2-(5-Bromo-2-ethoxybenzenesulfonyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid; 3-Carboxy-2-(5-bromo-2-ethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline; Tetrahydroisoquinoline-3-carboxylic acid sulfonamide derivative
EINECS	Contact for details

Quality Control

Our production of 2-(5-Bromo-2-Ethoxy-Benzenesulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.