Description

Isoxazol-4-Ylboronic Acid CAS NO 1008139-25-0 is a high-purity boronic acid derivative featuring an isoxazole heterocycle, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and advanced intermediates. Its specific structure facilitates the introduction of the isoxazole pharmacophore into target molecules, making it invaluable for drug discovery and material science programs.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing the isoxazole moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Employed in the creation of organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Research: A versatile reagent in academic and industrial R&D for methodology development and library synthesis via cross-coupling reactions.
• Ligand Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	Isoxazol-4-Ylboronic Acid
CAS No.	1008139-25-0
Molecular Formula	C3H4BNO3
Molecular Weight	112.88 g/mol
Synonyms	4-Isoxazoleboronic Acid; (Isoxazol-4-yl)boronic Acid; 4-Boronoisoxazole; Isoxazole-4-boronic Acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole (Pinacol ester precursor); 1008139-25-0; B-(Isoxazol-4-yl)boronic Acid
EINECS	Contact for details

Quality Control

Our Isoxazol-4-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider keeping the container under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.