Description

2-(4-Ethoxy-Benzenesulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonylated tetrahydroisoquinoline carboxylic acid structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Protease Inhibitor Development: Its structural features make it relevant for research into inhibitors of specific enzymes like proteases.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis: Serves as a starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client research.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-(4-Ethoxy-Benzenesulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
CAS No.	1008091-79-9
Molecular Formula	C18H19NO5S
Molecular Weight	361.41 g/mol
Synonyms	2-[(4-Ethoxyphenyl)sulfonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 1,2,3,4-Tetrahydro-2-[(4-ethoxyphenyl)sulfonyl]-3-isoquinolinecarboxylic Acid; 2-(4-Ethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 1008091-79-9; AI3-52335; SCHEMBL23346877; ZINC000006049007; AKOS040759623.
EINECS	Contact for details

Quality Control

Our production of 2-(4-Ethoxy-Benzenesulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.