Description

1-[(5-Chlorothien-2-Yl)Sulfonyl]Piperidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic sulfonamide structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring complex, functionalized piperidine scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Protease Inhibitor Development: Its structural features make it relevant for research into inhibitors for specific enzyme classes.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological processes and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	1-[(5-Chlorothien-2-Yl)Sulfonyl]Piperidine-2-Carboxylic Acid
CAS No.	1008038-62-7
Molecular Formula	C10H12ClNO4S2
Molecular Weight	309.79 g/mol
Synonyms	1-[(5-Chlorothiophen-2-yl)sulfonyl]piperidine-2-carboxylic acid; 2-Piperidinecarboxylic acid, 1-[(5-chloro-2-thienyl)sulfonyl]-; 1-(5-Chlorothiophene-2-sulfonyl)piperidine-2-carboxylic acid; (5-Chlorothiophen-2-yl)(2-carboxypiperidin-1-yl)sulfone; 1-(5-Chloro-2-thienylsulfonyl)piperidine-2-carboxylic acid; 1-(5-Chlorothiophene-2-sulfonyl)-2-piperidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[(5-Chlorothien-2-Yl)Sulfonyl]Piperidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) to support your research and development or cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.