Description

1-[(5-Chloro-2-Thienyl)Sulfonyl]Proline is a specialized proline derivative featuring a chlorothiophene sulfonyl group, making it a valuable synthetic intermediate and building block in advanced organic chemistry. This compound is critical for research and development in pharmaceutical chemistry, particularly for the synthesis of novel bioactive molecules and enzyme inhibitors. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly protease inhibitors and other enzyme-targeted therapies.
• Chemical Biology Research: Used in the development of chemical probes and activity-based protein profiling (ABPP) reagents to study enzyme function.
• Peptidomimetic Synthesis: Serves as a constrained proline analog for creating novel peptidomimetics with enhanced metabolic stability and binding affinity.
• Agrochemical Research: Intermediate in the development of new active ingredients for crop protection products.
• Material Science: Potential precursor for functionalized polymers or advanced organic materials with specific electronic properties.

Basic Information

Product Name	1-[(5-Chloro-2-Thienyl)Sulfonyl]Proline
CAS No.	1007999-30-5
Molecular Formula	C9H10ClNO4S2
Molecular Weight	295.76 g/mol
Synonyms	1-[(5-Chloro-2-thienyl)sulfonyl]-L-proline; (S)-1-((5-Chlorothiophen-2-yl)sulfonyl)pyrrolidine-2-carboxylic acid; L-Proline, 1-[(5-chloro-2-thienyl)sulfonyl]-; 1-(5-Chlorothiophene-2-sulfonyl)proline; Proline, 1-[(5-chloro-2-thienyl)sulfonyl]-; 1007999-30-5; 5-Chloro-2-thiophenesulfonylproline
EINECS	Contact for details

Quality Control

Our 1-[(5-Chloro-2-Thienyl)Sulfonyl]Proline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.