Description

2-(Furan-2-Carbonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its fused isoquinoline and furan carbonyl structure. This compound is of significant value for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the creation of novel therapeutic agents, including potential candidates for central nervous system (CNS) and oncology applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and validation in QC laboratories.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and pharmacological studies due to its reactive carboxylic acid group.
• Academic & Institutional Research: Employed in universities and research institutes for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-(Furan-2-Carbonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
CAS No.	1007979-03-4
Molecular Formula	C₁₅H₁₃NO₄
Molecular Weight	271.27 g/mol
Synonyms	1,2,3,4-Tetrahydro-2-(2-furoyl)-3-isoquinolinecarboxylic Acid; 2-(2-Furoyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid; 3-Carboxy-1,2,3,4-tetrahydro-2-(2-furoyl)isoquinoline; 2-(Furan-2-carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; Furoyl-THIQ-3-COOH
EINECS	Contact for details

Quality Control

Our 2-(Furan-2-Carbonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.