Description

2-(Dimethylamino)-2-(Thiophen-2-Yl)Acetic Acid is a specialized chiral α-amino acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, combining a thiophene heterocycle with a dimethylamino acetic acid moiety, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Intermediate in the development of organic semiconductors, conductive polymers, and other functional organic materials.
• Chemical Biology Probes: Used to create labeled compounds or molecular probes for studying biological pathways and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific chiral scaffold.

Basic Information

Product Name	2-(Dimethylamino)-2-(Thiophen-2-Yl)Acetic Acid
CAS No.	1007878-98-9
Molecular Formula	C10H13NO2S
Molecular Weight	211.28 g/mol
Synonyms	2-(Dimethylamino)-2-(2-thienyl)acetic acid; 2-(2-Thienyl)-2-(dimethylamino)acetic acid; α-(Dimethylamino)-2-thiopheneacetic acid; 2-Thiopheneglycine, N,N-dimethyl-; (2-Thienyl)(dimethylamino)acetic acid; DMTA; DMTAA
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, ensuring batch-to-batch consistency and traceability. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.