Description

Benzenemethanol, 3-[2-(Trimethylsilyl)Ethynyl]- is a specialized organosilicon building block featuring a trimethylsilyl-protected ethynyl group attached to a benzyl alcohol core. This compound matters as a versatile synthetic intermediate, enabling the controlled introduction of an alkyne moiety into complex molecular architectures under mild conditions. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as Sonogashira coupling reactions and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides that require alkyne-functionalized aromatic components.
• Material Science: Serves as a monomer or precursor for polymers and advanced organic materials with tailored electronic or optical properties.
• Organic Synthesis: A versatile reagent for Sonogashira, Heck, and other palladium-catalyzed coupling reactions to construct complex organic molecules.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Used in academic and industrial R&D for exploring new synthetic methodologies and creating molecular libraries.

Basic Information

Product Name	Benzenemethanol, 3-[2-(Trimethylsilyl)Ethynyl]-
CAS No.	1007587-63-4
Molecular Formula	C₁₂H₁₆OSi
Molecular Weight	204.34 g/mol
Synonyms	3-[(Trimethylsilyl)ethynyl]benzyl alcohol; 3-(2-Trimethylsilylethynyl)benzenemethanol; m-(Trimethylsilylethynyl)benzyl alcohol; (3-(Hydroxymethyl)phenyl)ethynyltrimethylsilane; TMS-Ethynylbenzyl Alcohol; 3-(Trimethylsilylethynyl)phenylmethanol; 3-(2-(Trimethylsilyl)ethynyl)benzyl alcohol
EINECS	Contact for details

Quality Control

Our Benzenemethanol, 3-[2-(Trimethylsilyl)Ethynyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.