Description

α-Ketobutyric Acid-D2 Sodium Salt is a high-purity, deuterium-labeled derivative of α-ketobutyric acid, specifically designed for advanced research and analytical applications. This stable isotope-labeled compound is critical for metabolic pathway studies, providing a non-radioactive tracer for precise quantification and mechanistic investigations. It is an essential reagent for researchers and scientists in pharmaceutical development, biochemistry, and metabolic research who require reliable, high-quality isotopic standards.

Application

• Metabolic Tracer Studies: Used as a deuterium-labeled internal standard in mass spectrometry (MS) for the accurate quantification of α-ketobutyric acid and related metabolites in biological samples.
• Biochemical Research: Employed in enzymatic assays and studies of metabolic pathways, including the methionine salvage cycle and threonine metabolism.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development and analysis of drugs targeting metabolic disorders.
• Stable Isotope Labeling: Essential for Nuclear Magnetic Resonance (NMR) spectroscopy and isotope dilution analysis to track metabolic fluxes.
• Nutritional Science: Applied in research investigating amino acid metabolism and nutritional biomarkers.
• Diagnostic Agent Development: Potential use in creating labeled compounds for in-vitro diagnostic assays.

Basic Information

Product Name	α-Ketobutyric Acid-D2 Sodium Salt
CAS No.	1007476-82-5
Molecular Formula	C4H3D2NaO3
Molecular Weight	130.08 g/mol
Synonyms	2-Oxobutyric Acid-d2 Sodium Salt; Sodium 2-Oxobutyrate-d2; α-Ketobutyric Acid-d2 Sodium Salt; 2-Oxobutanoic Acid-d2 Sodium Salt; Sodium α-Ketobutyrate-d2; 2-Ketobutyric Acid-d2 Sodium Salt; Deuterated α-Ketobutyrate Sodium Salt; (2,2-Dideutero-2-oxobutanoato)sodium
EINECS	Contact for details

Quality Control

Every batch of α-Ketobutyric Acid-D2 Sodium Salt is manufactured and tested under strict quality management systems to ensure the highest isotopic and chemical purity for research applications. Our products undergo rigorous analytical testing, including NMR, HPLC, and MS, to confirm identity, chemical purity, and isotopic enrichment. Certificates of Analysis (COA) detailing lot-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.