Description

Methyl 1-(Trifluoromethyl)Isoquinoline-3-Carboxylate is a high-value, fluorinated isoquinoline derivative that serves as a critical building block in advanced organic synthesis. Its core value lies in the trifluoromethyl group, which imparts unique electronic and metabolic properties to target molecules, making them more lipophilic and bioavailable. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: A versatile reagent for constructing complex heterocyclic frameworks in medicinal and process chemistry.
• Ligand & Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Methyl 1-(Trifluoromethyl)Isoquinoline-3-Carboxylate
CAS No.	1006707-71-6
Molecular Formula	C12H8F3NO2
Molecular Weight	255.19 g/mol
Synonyms	Methyl 1-(trifluoromethyl)-3-isoquinolinecarboxylate; 1-(Trifluoromethyl)isoquinoline-3-carboxylic acid methyl ester; 3-Carbomethoxy-1-trifluoromethylisoquinoline; 1-Trifluoromethylisoquinoline-3-carboxylic Acid Methyl Ester; Methyl 1-Trifluoromethyl-3-isoquinolinecarboxylate; 1-Trifluoromethyl-3-methoxycarbonylisoquinoline; 1-(Trifluoromethyl)-3-(methoxycarbonyl)isoquinoline
EINECS	Contact for details

Quality Control

Our Methyl 1-(Trifluoromethyl)Isoquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.