Description

5-(2,3-Dihydro-1H-Indol-1-Ylcarbonyl)-1-Methyl-1H-Pyrazole-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for complex active pharmaceutical ingredients.
• Biochemical Research: Potential tool compound for investigating specific biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and drug discovery projects.

Basic Information

Product Name	5-(2,3-Dihydro-1H-Indol-1-Ylcarbonyl)-1-Methyl-1H-Pyrazole-4-Carboxylic Acid
CAS No.	1006476-71-6
Molecular Formula	C14H13N3O3
Molecular Weight	271.27 g/mol
Synonyms	1-Methyl-5-(2,3-dihydro-1H-indole-1-carbonyl)-1H-pyrazole-4-carboxylic acid; 1-Methyl-5-(indolin-1-ylcarbonyl)-1H-pyrazole-4-carboxylic acid; 5-(Indoline-1-carbonyl)-1-methyl-1H-pyrazole-4-carboxylic acid; 5-(2,3-Dihydroindole-1-carbonyl)-1-methylpyrazole-4-carboxylic acid; 1-Methyl-5-(2,3-dihydro-1H-indol-1-ylcarbonyl)-1H-pyrazole-4-carboxylic acid; 1006476-71-6; UNII-9Q8C2J8J8H
EINECS	Contact for details

Quality Control

Our 5-(2,3-Dihydro-1H-Indol-1-Ylcarbonyl)-1-Methyl-1H-Pyrazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal quality standards and regulatory requirements for research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.