Description

5-[(3-Nitro-1H-Pyrazol-1-Yl)Methyl]Thiophene-2-Carboxylic Acid CAS NO 1006457-74-4 is a high-purity, heterocyclic carboxylic acid derivative featuring a nitro-substituted pyrazole moiety. This compound serves as a critical building block in advanced organic synthesis, enabling the development of novel molecular architectures. It is primarily required by pharmaceutical R&D and agrochemical research organizations for the creation of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drug candidates, particularly in therapeutic areas targeting enzyme inhibition.
• Agrochemical Research: Used in the synthesis of advanced pesticide and herbicide prototypes, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for functional polymers and organic electronic materials due to the electron-withdrawing nitro and carboxylic acid groups.
• Chemical Biology: Employed as a molecular probe or linker in bioconjugation and proteomics research.
• Academic & Industrial R&D: A versatile reagent for methodological studies in organic chemistry and heterocycle synthesis.

Basic Information

Product Name	5-[(3-Nitro-1-H-Pyrazol-1-Yl)Methyl]Thiophene-2-Carboxylic Acid
CAS No.	1006457-74-4
Molecular Formula	C10H7N3O4S
Molecular Weight	265.25 g/mol
Synonyms	5-[(3-Nitro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-[(3-nitro-1H-pyrazol-1-yl)methyl]-; 5-((3-Nitro-1H-pyrazol-1-yl)methyl)thiophene-2-carboxylic acid; 1-(2-Carboxythiophen-5-ylmethyl)-3-nitropyrazole; 5-[(3-Nitro-1H-pyrazol-1-yl)methyl]-2-thiophenecarboxylic acid; 5-(3-Nitro-1H-pyrazol-1-ylmethyl)thiophene-2-carboxylic acid; 1006457-74-4
EINECS	Contact for details

Quality Control

Our production of 5-[(3-Nitro-1H-Pyrazol-1-Yl)Methyl]Thiophene-2-Carboxylic Acid adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and undergoes rigorous analytical testing, including HPLC and NMR, to confirm identity and purity. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.