Description

5-(4-Nitro-Pyrazol-1-Ylmethyl)-Thiophene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining pyrazole and thiophene moieties. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new crop protection agents and pesticides with specific activity profiles.
• Material Science: Potential monomer or additive for developing specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.

Basic Information

Product Name	5-(4-Nitro-Pyrazol-1-Ylmethyl)-Thiophene-2-Carboxylic Acid
CAS No.	1006457-69-7
Molecular Formula	C10H7N3O4S
Molecular Weight	265.25 g/mol
Synonyms	5-[(4-Nitro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid; 5-((4-Nitro-1H-pyrazol-1-yl)methyl)thiophene-2-carboxylic acid; 1-(Thiophen-2-ylmethyl)-4-nitro-1H-pyrazole-5-carboxylic acid (tautomeric form); 5-(4-Nitro-1-pyrazolylmethyl)-2-thiophenecarboxylic acid; 1006457-69-7; 5-(4-Nitropyrazol-1-ylmethyl)thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-(4-Nitro-Pyrazol-1-Ylmethyl)-Thiophene-2-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements, from research to development scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep away from heat, sparks, and open flames. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.