Description

5-(3,4-Dihydroisoquinolin-2(1H)-Ylcarbonyl)-1-Methyl-1H-Pyrazole-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it offers a critical building block for medicinal chemistry research and development, enabling the creation of novel therapeutic agents with high structural precision. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing new drug candidates, particularly in areas targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop novel bioactive compounds.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for chemical biology and drug discovery projects.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot and commercial manufacturing scales.

Basic Information

Item	Detail
Product Name	5-(3,4-Dihydroisoquinolin-2(1H)-Ylcarbonyl)-1-Methyl-1H-Pyrazole-4-Carboxylic Acid
CAS No.	1006455-90-8
Molecular Formula	C15H15N3O3
Molecular Weight	285.30 g/mol
Synonyms	1-Methyl-5-[(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)]-1H-pyrazole-4-carboxylic acid; 1-Methyl-5-(1,2,3,4-tetrahydro-2-isoquinolinecarbonyl)-1H-pyrazole-4-carboxylic acid; 5-(1,2,3,4-Tetrahydroisoquinoline-2-carbonyl)-1-methyl-1H-pyrazole-4-carboxylic acid; 5-(3,4-Dihydro-1H-isoquinoline-2-carbonyl)-1-methyl-1H-pyrazole-4-carboxylic acid; 1-Methyl-5-(3,4-dihydro-1H-isoquinoline-2-carbonyl)-1H-pyrazole-4-carboxylic acid; 5-(3,4-Dihydroisoquinoline-2(1H)-ylcarbonyl)-1-methyl-1H-pyrazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(3,4-Dihydroisoquinolin-2(1H)-Ylcarbonyl)-1-Methyl-1H-Pyrazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.