Description

5-[(4-Chloro-1H-Pyrazol-1-Yl)Methyl]Thiophene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining pyrazole and thiophene moieties. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents or crop protection products.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in oncology, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the manufacture of modern pesticides, herbicides, and fungicides, leveraging its heterocyclic scaffold for bioactivity.
• Medicinal Chemistry Research: Provides a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes and tool compounds for target identification and validation in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the scale-up and production of client-specific molecules.
• Academic Research: Used in university and institutional laboratories for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-[(4-Chloro-1H-Pyrazol-1-Yl)Methyl]Thiophene-2-Carboxylic Acid
CAS No.	1006455-24-8
Molecular Formula	C9H7ClN2O2S
Molecular Weight	242.68 g/mol
Synonyms	5-[(4-Chloro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-[(4-chloro-1H-pyrazol-1-yl)methyl]-; 1006455-24-8; 5-((4-Chloro-1H-pyrazol-1-yl)methyl)thiophene-2-carboxylic acid; 5-[(4-Chloro-1H-pyrazol-1-yl)methyl]-2-thiophenecarboxylic acid; 5-(4-Chloro-pyrazol-1-ylmethyl)-thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-[(4-Chloro-1H-Pyrazol-1-Yl)Methyl]Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.