Description

3-Amino-4-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant commercial interest. Its value lies in its versatile chemical structure, which serves as a critical intermediate in the synthesis of complex, high-value molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to construct novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyrazole core for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Specialty Chemical Production: Employed in the manufacture of dyes, pigments, and advanced materials requiring specific heterocyclic architectures.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of client-specific target molecules under cGMP conditions where applicable.

Basic Information

Product Name	3-Amino-4-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid
CAS No.	1006451-86-0
Molecular Formula	C5H6ClN3O2
Molecular Weight	175.57 g/mol
Synonyms	4-Chloro-1-methyl-1H-pyrazole-5-carboxylic acid, 3-amino-; 3-Amino-4-chloro-1-methylpyrazole-5-carboxylic acid; 1-Methyl-3-amino-4-chloropyrazole-5-carboxylic acid; ACMC-1C7VY; 4-Chloro-1-methyl-3-amino-1H-pyrazole-5-carboxylic acid; AKOS025310991; 1006451-86-0; 3-Amino-4-chloro-1-methyl-1H-pyrazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates, including those under development for regulatory submission.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.