Description

4-[(4-Chloro-1H-Pyrazol-1-Yl)Methyl]-5-Methylthiophene-2-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining pyrazole and thiophene moieties. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and anti-inflammatory research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Material Science: Serves as a precursor for functionalized organic materials and ligands in catalytic systems.
• Academic & R&D: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and corporate laboratories.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing tailored compounds for client projects.

Basic Information

Product Name	4-[(4-Chloro-1H-Pyrazol-1-Yl)Methyl]-5-Methylthiophene-2-Carbaldehyde
CAS No.	1006448-83-4
Molecular Formula	C10H9ClN2OS
Molecular Weight	240.71 g/mol
Synonyms	5-Methyl-4-[(4-chloro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxaldehyde; 4-[(4-Chloro-1H-pyrazol-1-yl)methyl]-5-methyl-2-thiophenecarboxaldehyde; 2-Thiophenecarboxaldehyde, 4-[(4-chloro-1H-pyrazol-1-yl)methyl]-5-methyl-; 1006448-83-4; 4-(4-Chloro-1H-pyrazol-1-ylmethyl)-5-methylthiophene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-[(4-Chloro-1H-Pyrazol-1-Yl)Methyl]-5-Methylthiophene-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere when appropriate. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.