Description

Methyl 3-Bromobenzo[B]Thiophene-5-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, where the bromine atom and ester group serve as orthogonal handles for selective functionalization, enabling the rapid construction of complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, ligand design, and the development of novel electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection products, leveraging the benzo[b]thiophene scaffold's bioactivity.
• Material Science Building Block: Serves as a monomer or precursor for constructing organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts due to its electron-rich thiophene core.
• Chemical Biology Probe Synthesis: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in cross-coupling reactions, ring-forming transformations, and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	Methyl 3-Bromobenzo[B]Thiophene-5-Carboxylate
CAS No.	1005206-97-2
Molecular Formula	C10H7BrO2S
Molecular Weight	271.13 g/mol
Synonyms	Methyl 3-bromobenzo[b]thiophene-5-carboxylate; 3-Bromo-5-(methoxycarbonyl)benzo[b]thiophene; 3-Bromobenzo[b]thiophene-5-carboxylic acid methyl ester; 5-Carbomethoxy-3-bromobenzo[b]thiophene; Methyl 3-bromo-1-benzothiophene-5-carboxylate; 3-Bromobenzo[b]thiophene-5-methyl carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromobenzo[B]Thiophene-5-Carboxylate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.