Description

1-(2,4-Dichloro-Benzyl)-4-Isothiocyanato-1H-Pyrazole is a specialized heterocyclic organic compound featuring a pyrazole core functionalized with both a 2,4-dichlorobenzyl group and a reactive isothiocyanate moiety. This unique structure makes it a critical building block (advanced intermediate) for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily required by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Research: Used as a building block for developing next-generation herbicides, fungicides, and insecticides, leveraging its dichlorophenyl and isothiocyanate functionalities.
• Chemical Biology Probe Development: The reactive isothiocyanate group allows for covalent modification of proteins, making it useful for creating activity-based probes in proteomics and biochemical research.
• Material Science Research: Potential intermediate for synthesizing specialized polymers or ligands with specific binding properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular scaffold.

Basic Information

Product Name	1-(2,4-Dichloro-Benzyl)-4-Isothiocyanato-1H-Pyrazole
CAS No.	1004193-57-0
Molecular Formula	C11H7Cl2N3S
Molecular Weight	284.16 g/mol
Synonyms	4-Isothiocyanato-1-[(2,4-dichlorophenyl)methyl]-1H-pyrazole; 1-(2,4-Dichlorobenzyl)-1H-pyrazole-4-isothiocyanate; 1-(2,4-Dichlorobenzyl)-4-isothiocyanatopyrazole; 1H-Pyrazole-4-isothiocyanate, 1-[(2,4-dichlorophenyl)methyl]-; 1004193-57-0; 1-(2,4-Dichlorobenzyl)pyrazole-4-isothiocyanate
EINECS	Contact for details

Quality Control

Our 1-(2,4-Dichloro-Benzyl)-4-Isothiocyanato-1H-Pyrazole is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.