Description

1-(4-Fluoro-Benzyl)-4-Isothiocyanato-1H-Pyrazole is a high-purity, functionalized pyrazole derivative designed for advanced chemical synthesis. This compound is a critical building block in pharmaceutical and agrochemical research, valued for its reactive isothiocyanate group and fluorinated benzyl moiety. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Development: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Chemical Biology Probe Synthesis: The reactive isothiocyanate group enables conjugation to biomolecules for target identification and validation studies.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific fluorinated heterocyclic scaffolds.

Basic Information

Item	Detail
Product Name	1-(4-Fluoro-Benzyl)-4-Isothiocyanato-1H-Pyrazole
CAS No.	1004193-48-9
Molecular Formula	C11H8FN3S
Molecular Weight	233.26 g/mol
Synonyms	4-Isothiocyanato-1-[(4-fluorophenyl)methyl]-1H-pyrazole; 1-[(4-Fluorophenyl)methyl]-4-isothiocyanato-1H-pyrazole; 1-(4-Fluorobenzyl)-1H-pyrazole-4-isothiocyanate; 1-(4-Fluorobenzyl)-4-isothiocyanatopyrazole; 4-Isothiocyanato-1-(4-fluorobenzyl)pyrazole; 1-(4-Fluorobenzyl)-4-isothiocyanato-pyrazole; 1-(4-Fluorobenzyl)pyrazole-4-isothiocyanate
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-Benzyl)-4-Isothiocyanato-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.