Description

4-Fluoro-1H-Indol-5-Amine is a fluorinated indole derivative that serves as a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where the introduction of fluorine atoms can significantly alter biological activity and metabolic stability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated indole scaffold.
• Material Science Research: Acts as a precursor for organic electronic materials and specialty dyes due to its conjugated indole structure.
• Biochemical Research: Employed as a probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Academic & Contract Research: Serves as a valuable reagent for synthetic methodology development and novel heterocyclic chemistry exploration.

Basic Information

Product Name	4-Fluoro-1H-Indol-5-Amine
CAS No.	1003858-66-9
Molecular Formula	C8H7FN2
Molecular Weight	150.16 g/mol
Synonyms	5-Amino-4-fluoro-1H-indole; 4-Fluoro-1H-indol-5-amine; 4-Fluoroindol-5-amine; 1H-Indol-5-amine, 4-fluoro-; 4-Fluoro-5-aminoindole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1H-Indol-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.