Description

2-(tert-Butoxycarbonyl)Phenylboronic Acid is a specialized organoboron compound featuring a protected carboxylic acid group, making it a valuable intermediate in modern synthetic chemistry. Its core value lies in its dual functionality, allowing for selective chemical transformations, particularly in cross-coupling reactions, which are fundamental to constructing complex molecular architectures. This high-purity building block is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable and consistent reagents for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boronic acid partner for forming carbon-carbon bonds with aryl halides, a cornerstone reaction in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed processes.
• Material Science Research: A precursor for creating organic electronic materials and polymers with specific properties.
• Peptide Modification: Utilized for the site-specific introduction of boronic acid functionality into peptides and related biomolecules.
• Chemical Biology Probes: Acts as a starting material for synthesizing probes used in studying biological processes.

Basic Information

Item	Details
Product Name	2-(tert-Butoxycarbonyl)Phenylboronic Acid
CAS No.	1003043-25-1
Molecular Formula	C11H15BO4
Molecular Weight	222.05 g/mol
Synonyms	Boc-Protected Phenylboronic Acid; 2-Boc-Phenylboronic Acid; (2-((tert-Butoxycarbonyl)oxy)phenyl)boronic Acid; tert-Butyl 2-boronobenzoate; 2-(Boc)Phenylboronic Acid; 2-Carboxytert-butoxyphenylboronic Acid; [2-(tert-Butoxycarbonyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Every batch of our 2-(tert-Butoxycarbonyl)Phenylboronic Acid is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, with specifications typically meeting or exceeding industry standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.