Description

Ethyl 7-(Trifluoromethyl)-1-benzothiophene-2-carboxylate is a high-value, fluorinated heterocyclic building block designed for advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate the unique properties of the trifluoromethylated benzothiophene scaffold.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting various therapeutic areas, leveraging the metabolic stability and lipophilicity imparted by the trifluoromethyl group.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the benzothiophene core can contribute to biological activity.
• Material Science: Serves as a monomer or building block for creating specialty polymers and organic electronic materials with tailored properties.
• Chemical Synthesis: Employed in cross-coupling reactions, cyclizations, and as a versatile ester for further functional group transformations in medicinal chemistry.
• Ligand & Catalyst Development: Potential use in constructing novel ligands for catalysis or as a core structure in functional materials.

Basic Information

Item	Details
Product Name	Ethyl 7-(Trifluoromethyl)-1-benzothiophene-2-carboxylate
CAS No.	1002355-89-6
Molecular Formula	C₁₂H₉F₃O₂S
Molecular Weight	274.26 g/mol
Synonyms	Ethyl 7-(trifluoromethyl)benzo[b]thiophene-2-carboxylate; 1-Benzothiophene-2-carboxylic acid, 7-(trifluoromethyl)-, ethyl ester; Ethyl 7-trifluoromethyl-1-benzothiophene-2-carboxylate; 7-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid ethyl ester; 2-Carbethoxy-7-trifluoromethylbenzothiophene
EINECS	Contact for details

Quality Control

Our Ethyl 7-(Trifluoromethyl)-1-benzothiophene-2-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.