Description

tert-Butyl 5-(Hydroxymethyl)Thiazol-2-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its thiazole core and protected carbamate functionality. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of target drug molecules, particularly those containing thiazole heterocycles.
• API Synthesis: Used in the research and development of new Active Pharmaceutical Ingredients (APIs) for various therapeutic areas.
• Medicinal Chemistry Research: Serves as a crucial building block for constructing molecular libraries and exploring structure-activity relationships (SAR) in drug discovery.
• Bioconjugation & Prodrug Development: The hydroxymethyl group offers a handle for further chemical modification, linking, or prodrug strategy implementation.
• Chemical Biology Probes: Can be utilized in the synthesis of specialized probes for studying biological targets and pathways.

Basic Information

Product Name	tert-Butyl 5-(Hydroxymethyl)Thiazol-2-Ylcarbamate
CAS No.	1001419-37-9
Molecular Formula	C9H14N2O3S
Molecular Weight	230.28 g/mol
Synonyms	2-Thiazolecarbamic acid, 5-(hydroxymethyl)-, 1,1-dimethylethyl ester; tert-Butyl 5-(hydroxymethyl)-2-thiazolylcarbamate; 5-(Hydroxymethyl)-N-(tert-butoxycarbonyl)thiazol-2-amine; BOC-5-(Hydroxymethyl)thiazol-2-amine; 2-((tert-Butoxycarbonyl)amino)-5-(hydroxymethyl)thiazole; tert-Butyl N-[5-(hydroxymethyl)-1,3-thiazol-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-(Hydroxymethyl)Thiazol-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.