Description

4-Bromo-1-{[3-(Trifluoromethyl)Phenyl]Sulfonyl}-1H-Indole is a high-value, multi-functional chemical building block characterized by its bromo-indole core and trifluoromethylphenylsulfonyl protecting group. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active compounds and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the indole scaffold.
• Material Science: Acts as a precursor for functionalized organic molecules used in organic electronics and advanced polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in university and CRO laboratories.
• Custom Synthesis: A starting point for the tailored production of more complex, sulfonylated heterocyclic compounds for client-specific projects.

Basic Information

Product Name	4-Bromo-1-{[3-(Trifluoromethyl)Phenyl]Sulfonyl}-1H-Indole
CAS No.	1001394-81-5
Molecular Formula	C15H9BrF3NO2S
Molecular Weight	404.20 g/mol
Synonyms	4-Bromo-1-[(3-(trifluoromethyl)phenyl)sulfonyl]-1H-indole; 1H-Indole, 4-bromo-1-[[3-(trifluoromethyl)phenyl]sulfonyl]-; 4-Bromo-1-(3-trifluoromethylbenzenesulfonyl)indole; 4-Bromo-1-(3-(trifluoromethyl)phenylsulfonyl)indole; 4-Bromo-1-tosyl-1H-indole (3-CF3 analog); BTSI derivative
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-1-{[3-(Trifluoromethyl)Phenyl]Sulfonyl}-1H-Indole is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound should be considered moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.