Description

Zaleplon-D5 is a deuterated internal standard of the sedative-hypnotic agent Zaleplon, specifically designed for analytical applications. This high-purity, isotopically labeled compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry and other analytical techniques. It is primarily used by pharmaceutical research and development laboratories, contract research organizations (CROs), and quality control departments for method development, validation, and bioanalytical studies.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of Zaleplon in pharmacokinetic, bioavailability, and bioequivalence studies.
• Metabolite Analysis: Used as a reference standard in the identification and quantification of Zaleplon metabolites in biological matrices.
• Pharmaceutical Quality Control: Ensures batch-to-batch consistency and purity verification of active pharmaceutical ingredients (APIs) and finished drug products.
• Forensic and Clinical Toxicology: Supports accurate measurement of Zaleplon levels in forensic investigations and therapeutic drug monitoring.
• Method Development and Validation: Serves as a key component in developing robust, sensitive, and specific analytical methods compliant with regulatory guidelines (e.g., FDA, EMA).
• Stability Studies: Aids in assessing the stability profile of Zaleplon under various storage and stress conditions.

Basic Information

Product Name	Zaleplon-D5
CAS No.	1001083-56-2
Molecular Formula	C17H10D5N5O
Molecular Weight	312.38 g/mol
Synonyms	Zaleplon-d5; [D5]-Zaleplon; N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethyl-2,2,2-trideuteroacetamide-d2; Deuterated Zaleplon; Zaleplon (phenyl-d5); Sonata-d5; CL 284,846-d5; Internal Standard for Zaleplon
EINECS	Contact for details

Quality Control

Every batch of Zaleplon-D5 is manufactured and tested under strict quality management systems to ensure the highest standards of purity and isotopic enrichment. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic analyses, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.