Description

1H-Pyrrolo[2,3-B]Pyridine, 6-Bromo-1-(Phenylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated and sulfonated pyrrolopyridine core structure. This compound is of significant value for enabling complex molecular transformations in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex heterocyclic compounds for drug discovery programs.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization, particularly in kinase inhibitor and oncology research.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Agrochemical Synthesis: Potential intermediate for creating novel crop protection agents with specific biological activity.
• Material Science Research: Can be investigated as a precursor for organic electronic materials due to its conjugated heterocyclic system.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 6-Bromo-1-(Phenylsulfonyl)-
CAS No.	1001070-23-0
Molecular Formula	C13H9BrN2O2S
Molecular Weight	337.19 g/mol
Synonyms	6-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 6-Bromo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Phenylsulfonyl)-6-bromo-1H-pyrrolo[2,3-b]pyridine; 1-Benzenesulfonyl-6-bromo-1H-pyrrolo[2,3-b]pyridine; 6-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine (common alias); 6-Bromo-1H-pyrrolo[2,3-b]pyridine 1-(phenylsulfonyl) derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to strict internal quality management protocols to support our customers' needs for reliable and traceable materials in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.