Description

2-Amino-3-Carbamoyl-4,7-Dihydro-5H-Thieno[2,3-C]Pyridine-6-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex heterocyclic molecules, valued for its structural complexity and functional group versatility. It is primarily sought after by pharmaceutical R&D departments and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated nitrogen- and sulfur-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for constructing complex fused-ring systems containing thienopyridine cores.
• Research & Development (R&D): Employed in academic and industrial research laboratories for exploring new chemical entities and reaction pathways.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of target molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2-Amino-3-Carbamoyl-4,7-Dihydro-5H-Thieno[2,3-C]Pyridine-6-Carboxylic Acid tert-Butyl Ester
CAS No.	1001020-08-1
Molecular Formula	C₁₃H₁₇N₃O₃S
Molecular Weight	295.36 g/mol
Synonyms	tert-Butyl 2-amino-3-carbamoyl-4,7-dihydro-5H-thieno[2,3-c]pyridine-6-carboxylate; 2-Amino-3-carbamoyl-4,7-dihydro-5H-thieno[2,3-c]pyridine-6-carboxylic acid 1,1-dimethylethyl ester; 6-(tert-Butoxycarbonyl)-4,7-dihydro-5H-thieno[2,3-c]pyridine-2,3-dicarboxamide (tautomeric form); Thieno[2,3-c]pyridine-6-carboxylic acid derivative; CAS 1001020-08-1; BOC-protected thienopyridine intermediate
EINECS	Contact for details

Quality Control

Our production of 2-Amino-3-Carbamoyl-4,7-Dihydro-5H-Thieno[2,3-C]Pyridine-6-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured under controlled conditions suitable for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredient (API) starting materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.