Description

3-Chloropyridine-D4 is a deuterated isotopologue of 3-chloropyridine, where four hydrogen atoms are replaced by deuterium, a stable hydrogen isotope. This deuteration is critical for applications requiring reduced metabolic interference and enhanced analytical precision, such as in mass spectrometry and NMR spectroscopy. It serves as an essential building block and internal standard for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Research & Development: Used as a deuterated internal standard in quantitative LC-MS and GC-MS analysis for drug metabolism and pharmacokinetics (DMPK) studies.
• Agrochemical Synthesis: Acts as a labeled precursor in the development and environmental tracing of novel pesticides and herbicides.
• Metabolic Pathway Studies: Employed in mechanistic studies to track biochemical pathways without significant isotopic effect interference.
• NMR Spectroscopy Solvent & Reagent: Serves as a useful deuterated solvent or shift reagent in nuclear magnetic resonance spectroscopy.
• Material Science: Utilized in the synthesis of specialized deuterated polymers or liquid crystals for optoelectronic applications.
• Chemical Reference Standard: Provides a high-purity, isotopically labeled reference material for analytical method development and validation.

Basic Information

Product Name	3-Chloropyridine-D4
CAS No.	1001003-95-7
Molecular Formula	C5D4ClN
Molecular Weight	117.57 g/mol (approx.)
Synonyms	3-Chloro-D4-pyridine; Deuterated 3-Chloropyridine; 3-Chloropyridine-d4; Perdeuterated 3-Chloropyridine; 3-Chloropyridine (tetradeuterated); 3-Cl-pyridine-D4; β-Chloropyridine-D4; Pyridine-D4, 3-chloro-
EINECS	Contact for details

Quality Control

Our 3-Chloropyridine-D4 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and Mass Spectrometry, to confirm isotopic purity (D-enrichment) and chemical purity. Certificates of Analysis (COA) detailing assay, isotopic enrichment level, and impurity profiles are provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.