Description

2-Chloropyridine-D4 is a deuterated isotopologue of 2-chloropyridine, where four hydrogen atoms are replaced with deuterium. This compound is a critical stable isotope-labeled standard, essential for ensuring accuracy and reliability in quantitative analytical techniques. It is primarily used by researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors for applications such as internal standard calibration and metabolic studies.

Application

• Used as an internal standard in quantitative GC-MS and LC-MS analysis for accurate measurement of 2-chloropyridine and related compounds.
• Critical for metabolic pathway studies and drug metabolism research (DMPK) in pharmaceutical development.
• Employed in environmental analysis to trace and quantify chloropyridine derivatives in complex matrices.
• Facilitates method development and validation in analytical laboratories, improving reproducibility.
• Serves as a labeled precursor or intermediate in the synthesis of deuterated active pharmaceutical ingredients (APIs) and specialty chemicals.
• Applied in nuclear magnetic resonance (NMR) spectroscopy as a non-protonated solvent or tracer in mechanistic studies.

Basic Information

Product Name	2-Chloropyridine-D4
CAS No.	1001003-94-6
Molecular Formula	C5D4ClN
Molecular Weight	117.57 g/mol
Synonyms	2-Chloro-d4-pyridine; Deuterated 2-Chloropyridine; 2-Chloropyridine-2,3,5,6-d4; Perdeuterated 2-Chloropyridine; 2-Chloropyridine (D4); 2-Cl-Pyridine-D4; Pyridine-D4, 2-chloro-; 2-Chloropyridine-d4 (isotopic labeling agent)
EINECS	Contact for details

Quality Control

Every batch of 2-Chloropyridine-D4 is produced and analyzed under strict quality management protocols to ensure isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including spectroscopic and chromatographic analysis, to ensure compliance with industry standards for isotopic labeled compounds. Certificates of Analysis (COA) detailing isotopic enrichment (D atom %), chemical purity, and analytical methods are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.