Description

Benzene, 1-Bromo-4-(1,1-Difluoroethyl)- is a specialized halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a bromo-substituted benzene ring with a difluoroethyl moiety, making it a valuable precursor for introducing fluorinated groups into complex molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by material scientists developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides where the difluoroethyl group can enhance biological activity.
• Material Science: Serves as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D labs for exploring new cross-coupling reactions (e.g., Suzuki, Negishi) and as a scaffold for library synthesis in medicinal chemistry.
• Fluorine Chemistry: An essential reagent for studying structure-activity relationships (SAR) and for the development of new fluorination methodologies.

Basic Information

Item	Details
Product Name	Benzene, 1-Bromo-4-(1,1-Difluoroethyl)-
CAS No.	1000994-95-5
Molecular Formula	C8H7BrF2
Molecular Weight	221.04 g/mol
Synonyms	1-Bromo-4-(1,1-difluoroethyl)benzene; 4-Bromo-α,α-difluorotoluene; p-Bromo(1,1-difluoroethyl)benzene; (1,1-Difluoroethyl)-4-bromobenzene; 4-Bromobenzylidene difluoride; 1-Bromo-4-(difluoroethyl)benzene; α,α-Difluoro-4-bromoethylbenzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-4-(1,1-Difluoroethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.