Description

Boronic Acid, B-(1-Naphthalenyl-2,3,4,5,6,7,8-D7)- is a deuterium-labeled derivative of 1-naphthaleneboronic acid, a key building block in synthetic organic chemistry. This compound is specifically designed for applications requiring isotopic labeling, such as internal standards for mass spectrometry and mechanistic studies in drug metabolism and pharmacokinetics (DMPK). It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, isotopically enriched intermediates for precise analytical and synthetic work.

Application

• Pharmaceutical Research & Development: Used as a deuterium-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of active pharmaceutical ingredients (APIs) and metabolites.
• Drug Metabolism and Pharmacokinetics (DMPK): Critical for tracing metabolic pathways and conducting absorption, distribution, metabolism, and excretion (ADME) studies in preclinical research.
• Synthetic Organic Chemistry: Serves as a specialized building block in Suzuki-Miyaura cross-coupling reactions for the synthesis of deuterated complex molecules, including potential drug candidates and advanced materials.
• Agrochemical Development: Employed in the synthesis and analysis of deuterated pesticides or herbicides to study environmental fate and metabolic degradation.
• Academic & Institutional Research: Utilized in mechanistic studies and as a tracer in chemical reaction mechanisms within university and government laboratories.
• Material Science: Potential precursor for creating deuterated organic semiconductors or luminescent materials for optoelectronic devices.

Basic Information

Product Name	Boronic Acid, B-(1-Naphthalenyl-2,3,4,5,6,7,8-D7)-
CAS No.	1000869-26-0
Molecular Formula	C₁₀D₇BO₂
Molecular Weight	177.99 g/mol
Synonyms	(1-Naphthyl-d7)boronic Acid; 1-Naphthaleneboronic Acid-d7; B-(Naphthalen-1-yl-d7)boronic Acid; Deuteronated 1-Naphthaleneboronic Acid; 1-Naphthyl-d7-B(OH)₂; Naphthalene-1-boronic Acid-d7; Perdeuterated 1-Naphthylboronic Acid; (1-Naphthalenyl-d7)boronic Acid
EINECS	Contact for details

Quality Control

Our deuterated boronic acids are produced under strict quality control protocols to ensure isotopic purity and chemical integrity, critical for sensitive analytical applications. Each batch is characterized by advanced spectroscopic techniques including NMR (¹H, ¹³C, ¹¹B) and Mass Spectrometry to confirm deuteration level and chemical purity. Certificates of Analysis (COA) detailing isotopic enrichment (atom % D), chemical purity (by HPLC), and identity confirmation are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Isotopic Purity (Atom % D)	≥98.0% (by MS)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.