Description

[4-[2-(1H-Indazol-3-Yl)Ethenyl]Phenyl]-1-Piperazinylmethanone is a high-purity synthetic organic compound featuring a unique molecular architecture combining indazole and piperazine pharmacophores. This compound is of significant interest for its role as a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Used in the development and optimization of small molecule kinase inhibitors due to its indazole core structure.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead compound optimization.
• Biochemical Probe Development: Employed in the creation of tool compounds for studying specific biological targets and cellular processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for clinical trial materials.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	[4-[2-(1H-Indazol-3-Yl)Ethenyl]Phenyl]-1-Piperazinylmethanone
CAS No.	1000669-72-6
Molecular Formula	C22H22N4O
Molecular Weight	358.44 g/mol
Synonyms	1-({4-[(E)-2-(1H-Indazol-3-yl)ethenyl]phenyl}carbonyl)piperazine; (E)-1-(4-(2-(1H-Indazol-3-yl)vinyl)benzoyl)piperazine; 4-[2-(1H-Indazol-3-yl)vinyl]phenyl(piperazin-1-yl)methanone; 1-[4-[(E)-2-(1H-Indazol-3-yl)vinyl]benzoyl]piperazine; Piperazine, 1-[[4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]carbonyl]-
EINECS	Contact for details

Quality Control

Every batch of [4-[2-(1H-Indazol-3-Yl)Ethenyl]Phenyl]-1-Piperazinylmethanone is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.