Description

tert-Butyl 1-Bromo-6,7-dihydrothieno[3,4-c]pyridine-5(4H)-carboxylate is a high-value, protected heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with fused thienopyridine cores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• CNS Drug Development: Serves as a critical building block for molecules targeting neurological and psychiatric conditions.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Process Chemistry: Employed in route scouting and scale-up synthesis for advanced pharmaceutical intermediates.
• Agrochemical Research: Potential application in the synthesis of novel crop protection agents with heterocyclic motifs.
• Material Science: Exploration as a monomer or precursor for specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	tert-Butyl 1-Bromo-6,7-dihydrothieno[3,4-c]pyridine-5(4H)-carboxylate
CAS No.	1000577-96-7
Molecular Formula	C12H14BrNO2S
Molecular Weight	316.21 g/mol
Synonyms	1-Bromo-4,5,6,7-tetrahydrothieno[3,4-c]pyridine-5-carboxylic acid tert-butyl ester; tert-Butyl 1-bromo-4,5,6,7-tetrahydrothieno[3,4-c]pyridine-5-carboxylate; 5-tert-Butoxycarbonyl-1-bromo-4,5,6,7-tetrahydrothieno[3,4-c]pyridine; 1-Bromo-5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,4-c]pyridine; Boc-protected 1-bromothienopyridine; 1-Bromo-6,7-dihydro-4H-thieno[3,4-c]pyridine-5-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Bromo-6,7-dihydrothieno[3,4-c]pyridine-5(4H)-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.