Description

3-Cyano-1H-Indole-6-Carboxylic Acid Methyl Ester is a high-value indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both cyano and ester functional groups, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and pesticides with novel modes of action.
• Material Science: Serves as a monomer or building block for advanced polymers and organic electronic materials.
• Academic & R&D: Essential for methodological studies in organic synthesis and heterocyclic chemistry at universities and corporate labs.
• Fluorescent Probe Synthesis: Utilized in creating specialized indole-based dyes and sensors for biochemical assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Cyano-1H-Indole-6-Carboxylic Acid Methyl Ester
CAS No.	1000576-51-1
Molecular Formula	C11H8N2O2
Molecular Weight	200.20 g/mol
Synonyms	Methyl 3-cyano-1H-indole-6-carboxylate; 6-(Methoxycarbonyl)-1H-indole-3-carbonitrile; 1H-Indole-6-carboxylic acid, 3-cyano-, methyl ester; 3-Cyanoindole-6-carboxylic acid methyl ester; Methyl 3-cyanoindole-6-carboxylate; 6-Carbomethoxy-3-cyanoindole
EINECS	Contact for details

Quality Control

We maintain a stringent quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our standard grade typically meets a purity specification of ≥95% (by HPLC), with higher purity grades available upon request. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.