Description

(E)-3-(1H-Indol-7-Yl)Acrylamide is a high-purity, synthetic organic compound featuring a conjugated acrylamide moiety linked to an indole ring system. This specific molecular architecture makes it a valuable building block in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and pharmaceutical developers engaged in the discovery and development of novel bioactive molecules, particularly those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially those with indole-based structures.
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Probe Development: Serves as a starting material for synthesizing probes to study enzyme inhibition or receptor-ligand interactions in biological systems.
• Organic Synthesis: Employed in advanced organic reactions, such as Michael additions or polymerizations, leveraging its reactive acrylamide double bond.
• Agrochemical Research: Potential intermediate in the synthesis of novel crop protection agents and pesticides.

Basic Information

Product Name	(E)-3-(1H-Indol-7-Yl)Acrylamide
CAS No.	1000523-88-5
Molecular Formula	C11H10N2O
Molecular Weight	186.21 g/mol
Synonyms	(E)-3-(1H-Indol-7-yl)prop-2-enamide; 7-[(1E)-3-Amino-3-oxo-1-propen-1-yl]-1H-indole; (E)-3-(7-Indolyl)acrylamide; trans-3-(1H-Indol-7-yl)acrylamide; (E)-3-(Indol-7-yl)acrylamide; 2-Propenamide, 3-(1H-indol-7-yl)-, (2E)-; CAS 1000523-88-5
EINECS	Contact for details

Quality Control

Our (E)-3-(1H-Indol-7-Yl)Acrylamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.