Description

6,7-Difluoro-3-Hydroxy (1H)Indazole is a high-purity fluorinated indazole derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for modulating the biological activity and pharmacokinetic properties of target drug candidates. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of novel therapeutics, particularly in oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Used in research for creating potent and selective kinase inhibitors due to the indazole core's ability to mimic ATP.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides and pesticides, leveraging the stability imparted by fluorine atoms.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design of fluorescent or affinity probes to study enzyme function and protein interactions.

Basic Information

Product Name	6,7-Difluoro-3-Hydroxy (1H)Indazole
CAS No.	1000343-93-0
Molecular Formula	C7H4F2N2O
Molecular Weight	170.12 g/mol
Synonyms	3-Hydroxy-6,7-difluoro-1H-indazole; 6,7-Difluoro-1H-indazol-3-ol; 1H-Indazol-3-ol, 6,7-difluoro-; 6,7-Difluoroindazol-3-ol; 3-Hydroxy-6,7-difluoroindazole; 6,7-Difluoro-3-indazolol
EINECS	Contact for details

Quality Control

Our 6,7-Difluoro-3-Hydroxy (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.