Description

7-Chloro-5-Iodo (1H)Indazole is a halogenated indazole derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual halogen functionality, which provides distinct reactive sites for selective cross-coupling and functionalization reactions, enabling the construction of complex molecular architectures. This high-purity intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other biologically active heterocyclic compounds.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides with specific modes of action.
• Material Science: Serves as a building block for organic electronic materials, such as OLED emitters and charge transport layers.
• Chemical Biology: Employed as a molecular probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions.
• Ligand Synthesis: Utilized in the preparation of novel N-donor ligands for catalysis and coordination chemistry.

Basic Information

Product Name	7-Chloro-5-Iodo (1H)Indazole
CAS No.	1000343-56-5
Molecular Formula	C7H4ClIN2
Molecular Weight	278.48 g/mol
Synonyms	5-Iodo-7-chloro-1H-indazole; 7-Chloro-5-iodo-1H-indazole; 1H-Indazole, 7-chloro-5-iodo-; 7-Chloro-5-iodoindazole; 1000343-56-5
EINECS	Contact for details

Quality Control

Our 7-Chloro-5-Iodo (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.