Description

1-Acetyl-5-Bromo-7-Chloroindole is a high-purity, multi-halogenated indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which provides a versatile scaffold for constructing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with specific biological or functional properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used as a core structure for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Acts as a monomer or functional unit in the creation of specialized organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) agents.
• Academic & Contract Research: Serves as a valuable reagent for methodological development and exploration of new chemical spaces in university and CRO laboratories.

Basic Information

Product Name	1-Acetyl-5-Bromo-7-Chloroindole
CAS No.	1000343-44-1
Molecular Formula	C10H7BrClNO
Molecular Weight	272.52 g/mol
Synonyms	5-Bromo-7-chloro-1-acetylindole; 1-(5-Bromo-7-chloro-1H-indol-1-yl)ethanone; 1-Acetyl-5-bromo-7-chloro-1H-indole; 5-Bromo-7-chloroindole-1-acetic acid methyl ester derivative (common base name); ABI (abbreviation in research contexts); 7-Chloro-5-bromo-1-acetylindole; N-Acetyl-5-bromo-7-chloroindole
EINECS	Contact for details

Quality Control

Our 1-Acetyl-5-Bromo-7-Chloroindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High-Purity Grade)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.