Description

4-Bromo-3-Iodo-6-(Trifluoromethyl) (1H)Indazole is a high-value, multi-halogenated indazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines bromine, iodine, and a trifluoromethyl group on an indazole core, enabling precise structural modifications and the introduction of key functionalities. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in drug discovery programs targeting kinase inhibition and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the halogenated indazole scaffold.
• Material Science: Serves as a building block for creating specialized organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research due to its distinct halogen atoms for further functionalization.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	4-Bromo-3-Iodo-6-(Trifluoromethyl) (1H)Indazole
CAS No.	1000341-30-9
Molecular Formula	C8H3BrF3IN2
Molecular Weight	405.93 g/mol
Synonyms	4-Bromo-3-iodo-6-(trifluoromethyl)-1H-indazole; 1H-Indazole, 4-bromo-3-iodo-6-(trifluoromethyl)-; 4-Bromo-3-iodo-6-trifluoromethyl-1H-indazole; 6-(Trifluoromethyl)-4-bromo-3-iodo-1H-indazole; 4-Bromo-3-iodo-6-(trifluoromethyl)indazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Iodo-6-(Trifluoromethyl) (1H)Indazole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical development, ensuring data integrity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.