Description

3-Bromo-6-(Trifluoromethyl) (1H)Indazole is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs. Pharmaceutical, agrochemical, and advanced material researchers rely on this high-purity intermediate for its role in creating compounds with enhanced metabolic stability and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors, anticancer agents, and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides and pesticides leveraging the physicochemical properties of the trifluoromethyl group.
• Material Science: Serves as a precursor for advanced organic electronic materials and liquid crystals.
• Chemical Biology: Employed as a probe or labeling agent in biochemical studies due to its reactive bromine handle.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for client-specific molecular libraries.

Basic Information

Product Name	3-Bromo-6-(Trifluoromethyl) (1H)Indazole
CAS No.	1000341-21-8
Molecular Formula	C8H4BrF3N2
Molecular Weight	265.03 g/mol
Synonyms	3-Bromo-6-(trifluoromethyl)-1H-indazole; 1H-Indazole, 3-bromo-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-3-bromo-1H-indazole; 3-Bromo-6-trifluoromethylindazole; 3-Bromo-6-trifluoromethyl-1H-indazole; 1000341-21-8
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-(Trifluoromethyl) (1H)Indazole is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for research and development scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.