Description

1H-Indole, 6-Fluoro-4-Nitro- is a high-purity, fluorinated nitroindole derivative, a crucial advanced intermediate in modern synthetic organic chemistry. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific indole-based scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the indole core.
• Material Science Research: Serves as a monomer or functional component in the development of advanced organic electronic materials, dyes, and pigments.
• Biochemical Probe Development: Employed in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry and method development.

Basic Information

Product Name	1H-Indole, 6-Fluoro-4-Nitro-
CAS No.	1000340-83-9
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	6-Fluoro-4-nitro-1H-indole; 4-Nitro-6-fluoroindole; 6-Fluoro-4-nitroindole; 1H-Indole-6-fluoro-4-nitro; 6-Fluoro-4-nitro-1H-indole; 4-Nitro-6-fluoro-1H-indole; 6-Fluoro-4-nitroindole
EINECS	Contact for details

Quality Control

Our 1H-Indole, 6-Fluoro-4-Nitro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP starting materials and adherence to REACH regulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (argon or nitrogen) is recommended for optimal long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.