Description

4-Bromo-6-Chloro-3-Iodo-7-Azaindole is a highly functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its multi-halogenated structure makes it a versatile and valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by medicinal chemists and process development scientists working on kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its modifiable halogen handles.
• Cross-Coupling Reactions: Serves as a substrate for various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig) to introduce the azaindole core into more complex systems.
• Chemical Biology Probes: Utilized in the synthesis of chemical probes for studying biological pathways and protein function.
• Agrochemical Research: Potential intermediate in the discovery of new active ingredients for crop protection.
• Material Science: A building block for creating organic electronic materials and functional polymers.

Basic Information

Product Name	4-Bromo-6-Chloro-3-Iodo-7-Azaindole
CAS No.	1000340-78-2
Molecular Formula	C7H3BrClIN2
Molecular Weight	372.37 g/mol
Synonyms	4-Bromo-6-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-4-bromo-6-chloro-7-azaindole; 6-Chloro-4-bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 4-bromo-6-chloro-3-iodo-; 4-Bromo-6-chloro-3-iodo-1H-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-6-chloro-3-iodo-
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Chloro-3-Iodo-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder/crystals
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.