Description

6-Bromo-4-Chloro-3-Iodo-7-Azaindole is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its complex halogenated structure makes it a critical precursor for constructing sophisticated molecular architectures, particularly in pharmaceutical discovery and materials science. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of novel kinase inhibitors, anticancer agents, and other biologically active small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated indole core.
• Material Science Precursor: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-rich azaindole structure.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular tag in probe design.
• Cross-Coupling Reactions: The bromo and iodo substituents provide excellent handles for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Library Synthesis: A valuable starting material for generating diverse compound libraries in high-throughput screening for drug discovery.

Basic Information

Product Name	6-Bromo-4-Chloro-3-Iodo-7-Azaindole
CAS No.	1000340-68-0
Molecular Formula	C7H3BrClIN2
Molecular Weight	372.37 g/mol
Synonyms	4-Chloro-6-bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-6-bromo-4-chloro-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 6-bromo-4-chloro-3-iodo-; 6-Bromo-4-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 6-bromo-4-chloro-3-iodo-
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloro-3-Iodo-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.