Description

4-Bromo-3-Iodo-6-Methyl-7-Azaindole is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and iodine atoms on the azaindole core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, cross-coupling reactions, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The bromine and iodine substituents are excellent handles for Suzuki, Stille, and Sonogashira coupling reactions to create complex biaryl and conjugated systems.
• Medicinal Chemistry SAR Studies: Enables structure-activity relationship (SAR) exploration by allowing further functionalization at specific halogen sites.
• Chemical Biology Probes: Used in the synthesis of labeled compounds and molecular probes for biochemical and cellular studies.

Basic Information

Product Name	4-Bromo-3-Iodo-6-Methyl-7-Azaindole
CAS No.	1000340-56-6
Molecular Formula	C8H6BrIN2
Molecular Weight	352.96 g/mol
Synonyms	4-Bromo-3-iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine; 6-Methyl-4-bromo-3-iodo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-3-iodo-6-methyl-; 4-Bromo-3-iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 4-bromo-3-iodo-6-methyl-
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Iodo-6-Methyl-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to reliable supply and traceable documentation supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.