Description

5-Amino-4-Fluoro-3-Hydroxy (1H)Indazole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique indazole core, functionalized with amino, fluoro, and hydroxy groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Serves as a core structure for designing molecular probes to study biological pathways and enzyme functions.
• Material Science Precursor: Potential building block for advanced organic electronic materials and specialty polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library production.

Basic Information

Product Name	5-Amino-4-Fluoro-3-Hydroxy (1H)Indazole
CAS No.	1000340-49-7
Molecular Formula	C7H6FN3O
Molecular Weight	167.14 g/mol
Synonyms	4-Fluoro-5-amino-3-hydroxy-1H-indazole; 3-Hydroxy-5-amino-4-fluoro-1H-indazole; 1H-Indazol-3-ol, 5-amino-4-fluoro-; 5-Amino-4-fluoro-1H-indazol-3-ol; AFHI; 4-Fluoro-1H-indazol-3-ol, 5-amino-; 5-Amino-4-fluoroindazol-3-ol
EINECS	Contact for details

Quality Control

Our 5-Amino-4-Fluoro-3-Hydroxy (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.