Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 4-Cyano- is a high-value heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of kinase inhibitors and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A critical scaffold in the research and development of new drug candidates, especially for targeted cancer therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides with specific modes of action.
• Material Science Research: Serves as a building block for organic electronic materials and functional polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Academic & Contract Research: Essential for synthetic methodology development and exploration of new chemical space in university and CRO laboratories.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 4-Cyano-
CAS No.	1000340-46-4
Molecular Formula	C9H5N3O2
Molecular Weight	187.16 g/mol
Synonyms	4-Cyano-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 4-Cyano-7-azaindole-3-carboxylic acid; 4-CN-7-AzaIndole-3-COOH; 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 4-cyano-; 4-Cyano-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 7-Azaindole-3-carboxylic acid, 4-cyano-; AZD-9291 intermediate derivative; Osimertinib related compound B
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 4-Cyano- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.