Description

5-Amino-3-Chloro-4-Fluoro (1H)Indazole is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring amino, chloro, and fluoro substituents on the indazole core, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides and pesticides with enhanced efficacy.
• Material Science: Serves as a building block for advanced organic electronic materials and dyes.
• Chemical Biology: Employed as a probe or linker in the design of biochemical tools and diagnostic agents.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in academic and CRO settings.

Basic Information

Product Name	5-Amino-3-Chloro-4-Fluoro (1H)Indazole
CAS No.	1000340-45-3
Molecular Formula	C7H5ClFN3
Molecular Weight	185.59 g/mol
Synonyms	5-Amino-3-chloro-4-fluoro-1H-indazole; 3-Chloro-4-fluoro-1H-indazol-5-amine; 4-Fluoro-3-chloro-1H-indazol-5-amine; 1H-Indazole, 5-amino-3-chloro-4-fluoro-; AC-1H-Indazole-5-amine, 3-chloro-4-fluoro-; Building Block 1000340-45-3
EINECS	Contact for details

Quality Control

Our 5-Amino-3-Chloro-4-Fluoro (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to cGMP principles and reliable documentation supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.