Description

4-Bromo-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel pharmaceutical compounds and functional materials. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents, leveraging its versatile halogen handles for cross-coupling reactions.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, where the pyrrolopyridine scaffold can impart unique biological activity.
• Material Science: Serves as a building block for organic semiconductors, ligands for catalysis, and other functional organic materials due to its electron-rich heterocyclic structure.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry, including novel halogenation, cyclization, and cross-coupling methodologies.

Basic Information

Product Name	4-Bromo-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1000340-34-0
Molecular Formula	C7H4BrIN2
Molecular Weight	322.93 g/mol
Synonyms	4-Bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-3-iodo-; 4-Bromo-3-iodo-7-azaindole; 3-Iodo-4-bromo-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-3-iodo-1H-7-azaindole; 4-Br-3-I-7-azaindole; Halogenated 7-azaindole; Bromo-iodo pyrrolopyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO standards for pharmaceutical and research applications, ensuring reliable supply for critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate to ensure long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.